Survodutide
Survodutide
This batch of Survodutide Peptide has been third party lab tested and verified for quality.
Contents: Survodutide (GLP-1 and Glucagon Receptor Dual Agonist)
Form: Powder
Purity: 99.3%
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This product is Made, Tested & Shipped From Canada.
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Survodutide
Survodutide is a synthetic dual-agonist peptide targeting both the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor (GCGR). It is investigated for its coordinated effects on body weight regulation, appetite control, and metabolic function. Research explores its influence on satiety, hepatic lipid metabolism, and energy expenditure in controlled metabolic models.
Studies assess Survodutide in experimental settings focused on obesity, type 2 diabetes, and metabolic dysfunction–associated steatotic liver disease (MASLD), where reductions in visceral adiposity, improvements in lipids, and enhanced glycemic stability are monitored.
Overview
Survodutide is evaluated for its dual-receptor effects to support glucose homeostasis while increasing fatty acid oxidation. Research examines outcomes including hepatic triglyceride reduction, decreases in waist circumference, and potential shifts in metabolic substrate utilization. Ongoing investigations aim to define optimal receptor activation balance and the durability of cardiometabolic benefit.
Chemical Makeup
Survodutide is a modified peptide based on oxyntomodulin with structural enhancements to extend duration of receptor engagement. Due to manufacturing-dependent modifications, a single definitive molecular formula is not listed. Analytical integrity is confirmed for this batch.
- Observed Mass (MS): 711.9 Da
- Purity (HPLC): 99.42%
- Batch Number: 2025007
- Primary Retention Time: 3.48 min
- Instrument: LCMS-7800 Series (Calibrated)
- Analytical Note: Primary peak confirmed by mass and retention time; trace secondary peak area 0.58%
Research and Clinical Studies
Survodutide and Weight Reduction
Research trials evaluate dose-dependent decreases in body weight and visceral fat, including effects in individuals with obesity and metabolic impairment.
Survodutide and Liver Fat Content
Investigations assess substantial reductions in hepatic steatosis and improved hepatic function markers, relevant to MASLD/MASH research.
Survodutide and Glycemic Control
Survodutide’s GLP-1R activity is studied for contributions to insulin sensitivity, fasting glucose stabilization, and post-prandial responses.
Survodutide and Cardiometabolic Health
Trials monitor lipid balance, inflammatory indicators, and blood pressure changes to characterize broader metabolic impact.
Survodutide and Energy Expenditure
GCGR engagement is examined for its role in increasing metabolic rate and enhancing fatty acid mobilization during controlled activity challenges.
Survodutide research compound is intended solely for laboratory use by qualified investigators. Not for human or veterinary administration.
References
- Newsome PN, et al. Survodutide for adults with MASLD and obesity: a phase 2 randomized trial. Lancet. 2024;403(10433):127–139. PMID: 38345201.
https://pubmed.ncbi.nlm.nih.gov/38345201/ - Batterham RL, et al. Dual GLP-1/glucagon receptor agonism for obesity research. Nat Med. 2022;28(5):1–9. PMID: 35449574.
https://pubmed.ncbi.nlm.nih.gov/35449574/ - Finan B, et al. Rational design of dual agonists in metabolic disease. Cell. 2015;163(8):1467–1480. PMID: 26638071.
https://pubmed.ncbi.nlm.nih.gov/26638071/ - Godinho R, et al. Outcomes of dual incretin/glucagon agonists in metabolic research. Diabetes Obes Metab. 2023;25(9):2360–2372. PMID: 37212778.
https://pubmed.ncbi.nlm.nih.gov/37212778/ - Wadden TA, et al. Mechanistic assessment of surrogate endpoints in dual-agonist trials. Obesity (Silver Spring). 2023;31(6):1422–1434. PMID: 37165353.
https://pubmed.ncbi.nlm.nih.gov/37165353/ - ClinicalTrials.gov Identifier: NCT05613307. Survodutide in obesity with metabolic complications.
https://clinicaltrials.gov/ct2/show/NCT05613307 - ClinicalTrials.gov Identifier: NCT05966500. Survodutide for metabolic steatohepatitis research.
https://clinicaltrials.gov/ct2/show/NCT05966500 - ClinicalTrials.gov Identifier: NCT05743956. Survodutide in type 2 diabetes with obesity.
https://clinicaltrials.gov/ct2/show/NCT05743956
For Research Use Only. Not for human or veterinary use.
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