Selank
Selank
This batch of Selank Nootropic Peptide has been third party lab tested and verified for quality.
Contents: Selank
Form: Powder
Purity: 99.0%
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Selank Peptide
Selank is a synthetic peptide analog of the naturally occurring tetrapeptide tuftsin, developed to explore potential neuromodulatory and nootropic properties. It is a heptapeptide engineered to mimic tuftsin’s immunomodulatory actions while extending stability and activity. Researchers suggest Selank may influence both the central nervous system and peripheral processes, including neurotransmitter balance and stress-related pathways.
Overview
Selank has been studied in preclinical and clinical settings for its proposed ability to regulate neurotransmitters such as serotonin, dopamine, and norepinephrine. Evidence indicates that it may modulate the expression of genes linked to GABAergic signaling, potentially leading to anxiolytic-like effects. Some studies suggest Selank enhances memory consolidation, learning, and attention span in test models, aligning with its investigation as a nootropic compound.
Research has also proposed that Selank may influence the immune system. Early findings suggest a potential ability to alter cytokine production and support homeostatic regulation of immune responses. This dual action—neurological and immunological—makes Selank distinct among experimental peptides.
Chemical Makeup
- Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
- Molecular Formula: C33H57N11O9
- Molecular Weight: 751.9 g/mol
- Form: Lyophilized powder
- Purity: ≥ 99% (HPLC, batch verified)
Research and Clinical Studies
Selank and Anxiety
In experimental anxiety models, Selank has been shown to influence behavioral responses. Findings suggest its effect profile may resemble that of mild anxiolytic agents, without indications of sedation or dependence potential.
Selank and Cognitive Function
Animal studies report improvements in learning and memory tasks following Selank administration. These findings align with its proposed ability to modulate monoaminergic systems and neurotrophic expression.
Selank and Immune Regulation
Selank appears to impact immune responses by modulating cytokine production, particularly shifting the Th1/Th2 balance. This immunotropic activity is believed to stem from its tuftsin-derived sequence.
Selank and Neuroprotection
Early studies suggest Selank may exhibit neuroprotective effects through antioxidative processes and stabilization of neuronal metabolism. This is an area of ongoing research.
References
- Dolotov OV, et al. "Regulation of IL-6 and TNF-α expression in vitro by Selank." Bulletin of Experimental Biology and Medicine. 2006. https://pubmed.ncbi.nlm.nih.gov/17129980/
- Andreeva LA, et al. "Neurochemical study of Selank mechanism of action." Bulletin of Experimental Biology and Medicine. 2009. https://pubmed.ncbi.nlm.nih.gov/19795765/
- Zozulya AA, et al. "Immunomodulatory effects of Selank." Bulletin of Experimental Biology and Medicine. 2008. https://pubmed.ncbi.nlm.nih.gov/19198196/
- Ashmarin IP, et al. "Tuftsin and tuftsin analogues in neuroimmunomodulation." Ann N Y Acad Sci. 1998. https://pubmed.ncbi.nlm.nih.gov/9917873/
- Inozemtseva LS, et al. "Selank effect on learning and memory processes in rats." Neuroscience and Behavioral Physiology. 2008. https://pubmed.ncbi.nlm.nih.gov/18512018/
- Dolotov OV, et al. "Selank regulates the expression of genes related to neurotransmission and neuroplasticity." Bulletin of Experimental Biology and Medicine. 2011. https://pubmed.ncbi.nlm.nih.gov/21786662/
- Inozemtseva LS, et al. "Behavioral effects of Selank in animal models of stress and anxiety." Neuroscience and Behavioral Physiology. 2009. https://pubmed.ncbi.nlm.nih.gov/19334525/
- Zozulya AA, et al. "Tuftsin analogues as potential therapeutic peptides." Neurochemical Journal. 2011. https://pubmed.ncbi.nlm.nih.gov/22002448/
- Dolotov OV, et al. "Selank increases expression of BDNF in the hippocampus." Bulletin of Experimental Biology and Medicine. 2012. https://pubmed.ncbi.nlm.nih.gov/22997713/
- Ashmarin IP, et al. "Neuropeptides in adaptive regulation." Russian Journal of Physiology. 2005. https://pubmed.ncbi.nlm.nih.gov/16396488/
Certificate of Analysis (COA): Lab report for this product purity, identity, and chromatograms.
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