PT-141

Name: PT-141
Brand: Canada Peptides
Price: 43.0 CAD
Availability: InStock

$43.00

$43.00 ~~$56.00~~

Sold out

This batch of PT-141 Peptide has been third party lab tested and verified for quality.

Contents: PT-141
Form: Powder
Purity: 99.5%

TESTED FOR:

PURITY

WEIGHT

STERILITY

ENDOTOXINS(LPS)

Product variants

Quantity

Free Reconstitution Solution automatically added to your cart with each order.

This product is Made, Tested & Shipped From Canada.

🚚

Shipping & Delivery

We are committed to delivering fast, reliable, and transparent shipping for all orders. Please review our policy below for details on delivery times, tracking, and what to expect with every purchase.

View Full Shipping Policy

99%+ Purity Guaranteed

COA
Verified+

Trackable Shipping

View full details

PT-141 Peptide – 10mg
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH). It is a melanocortin receptor agonist with activity at MC3R and MC4R, studied for its effects on sexual behavior, central nervous system pathways, and melanocortin signaling. Unlike earlier melanocortin-based compounds, PT-141 has no significant activity at the MC1R receptor responsible for pigmentation, making it a distinct research tool for evaluating central melanocortin pathways.

Overview
PT-141 was developed through structural modification of the α-MSH analog melanotan II, optimizing its activity on central melanocortin receptors involved in sexual function and energy homeostasis. Preclinical studies have shown that PT-141 acts on hypothalamic neurons to regulate sexual behavior, arousal, and appetite pathways. It has been investigated in models of sexual dysfunction, metabolic regulation, and neuroendocrine signaling, with ongoing interest in its role in central nervous system research.

Chemical Makeup

Molecular Formula: C50H68N14O10
Molecular Weight: 1025.2 g/mol
Amino Acid Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH (cyclic lactam)
Other Known Titles: Bremelanotide, PT141 Peptide, Melanocortin Receptor Agonist

Research and Clinical Studies

Melanocortin System and Sexual Function
Animal studies have shown that PT-141 activates MC3R and MC4R receptors in the hypothalamus, resulting in enhanced sexual arousal and copulatory behavior in male and female models. Unlike phosphodiesterase type 5 inhibitors (PDE5i), PT-141 exerts its effects centrally rather than peripherally, making it a model compound for studying neuroendocrine sexual signaling.

Neuroendocrine and Appetite Regulation
The melanocortin system plays a key role in energy balance, and PT-141 has been studied for its influence on appetite suppression and body weight regulation in rodent models.

CNS Pharmacology and Safety
PT-141’s blood-brain barrier permeability and receptor selectivity have led to interest in its application for neuroendocrine and metabolic research. Early safety studies indicate a favorable pharmacological profile when administered intranasally or subcutaneously in controlled research settings.

Additional Research Applications
Exploratory studies have evaluated PT-141 for roles in ischemia protection, neuroinflammation modulation, and behavioral neuroscience research, making it a versatile model compound for melanocortin receptor biology.

PT-141 peptide is available for research and laboratory purposes only. Not for human consumption.

References

Dorr RT, et al. Melanocortin receptor agonists and sexual function: discovery of PT-141. Ann N Y Acad Sci. 2003;994:96–102. https://pubmed.ncbi.nlm.nih.gov/12851312/
Shadiack AM, et al. Melanocortin receptor agonists in sexual behavior research. Brain Res. 2007;1124(1):166–175. https://pubmed.ncbi.nlm.nih.gov/17118440/
Hadley ME, et al. Discovery and development of melanocortin receptor ligands. Ann N Y Acad Sci. 2006;994:1–15. https://pubmed.ncbi.nlm.nih.gov/12851309/
King SH, et al. PT-141: novel melanocortin analog in sexual arousal studies. J Sex Med. 2008;5(8):1939–1948. https://pubmed.ncbi.nlm.nih.gov/18624943/
Giuliano F, et al. Central melanocortin pathways and erectile function. Int J Impot Res. 2007;19(1):17–23. https://pubmed.ncbi.nlm.nih.gov/17043692/
Clayton AH, et al. Bremelanotide in female sexual dysfunction studies. J Sex Med. 2016;13(5):696–706. https://pubmed.ncbi.nlm.nih.gov/27045212/
Wessells H, et al. Central melanocortin modulation of sexual function in humans. J Urol. 2000;164(3 Pt 1):738–743. https://pubmed.ncbi.nlm.nih.gov/10953129/
van der Ploeg LH, et al. Melanocortin receptors and obesity research. Endocr Rev. 2002;23(6):728–743. https://pubmed.ncbi.nlm.nih.gov/12466191/
Kask A, et al. Melanocortins in the brain: from pigmentation to appetite. Eur J Pharmacol. 1999;375(1-3):1–12. https://pubmed.ncbi.nlm.nih.gov/10443489/
Wikberg JES, et al. Five subtypes of melanocortin receptors in energy homeostasis. Peptides. 1999;20(4):401–410. https://pubmed.ncbi.nlm.nih.gov/10328292/

Click to view

Page 1

Click to view

Page 1

SAFELY HANDLED
Products crafted in regulated, certified labs.
AIR PRIORITY
Fast and reliable 3-5 day shipping.
MANUAL ACCESS
Our knowledgeable team provides technical support 24/7.

Frequently Asked Questions

Here you'll find answers to common questions.

Contact our support team

Every vial we sell comes from a lab that follows current Good Manufacturing Practices (cGMP). That means each step of production is documented and controlled. Before a batch is released, it’s tested by independent third-party labs for purity, identity, and sterility. Certificates of analysis are available so you can see the exact test results.

Yes. The labs we work with use ISO-certified clean rooms where air quality, equipment, and handling procedures are tightly regulated. Staff are trained to pharmaceutical-grade standards. This ensures the peptides are produced in an environment that minimizes contamination risks.

Peptides in lyophilized (freeze-dried) form are stable at room temperature for transport. Once you receive them, refrigeration is recommended to maintain long-term integrity. We package every order securely to prevent damage and ship promptly, so your vials arrive in optimal condition.

We operate under strict in-house protocols that follow current Good Manufacturing Practices (cGMP). That means our team oversees the entire process from sourcing raw amino acids to the final lyophilized vial. Nothing is outsourced or repackaged. This gives us full control over purity, consistency, and sterility, and it’s why we can stand behind every single vial we ship.

Store them in the refrigerator, away from direct light and heat. If you need to keep them longer, some peptides can be stored frozen. Each vial comes with clear handling instructions so you know the proper conditions for stability.

The strongest proof is transparency. For every peptide, we can provide certificates of analysis, manufacturing documentation, and references to the published scientific research behind it. If you ever have questions, we’ll show you the data rather than ask you to take our word for it.

The difference is transparency. Most sites give you a product name and a price. We provide full batch testing, lab documentation, and direct access to certificates of analysis so you don’t have to guess what you’re getting. When you order from us, you know exactly what’s in the vial, where it was made, and how it was verified.

PT-141

PT-141

Shipping & Delivery

SAFELY HANDLED

AIR PRIORITY

MANUAL ACCESS

You may also like

Frequently Asked Questions

Age Verification Required